
In the evolving world of aesthetic medicine, the paradigm has shifted. We are moving away from the era of dramatic alterations and "frozen" expressions, gravitating instead towards a philosophy of regenerative aesthetics. At Retriva Aesthetic Clinic in Chelsea, we have always championed a "less is more" approach, focusing on enhancing your natural features rather than masking them.
If you are looking for a treatment that works beneath the surface to restore your skin's health from within, Polynucleotides are the gold standard. Often referred to as "the ultimate skin primer," these biostimulators are frequently the first step we recommend for patients seeking subtle, high-quality, and long-term rejuvenation.
To understand Polynucleotides, we must look at the cellular level. Unlike traditional injectables that provide instant volume, Polynucleotides are DNA-derived molecules: specifically fractions of DNA: that act as messengers to your skin cells.
When injected into the dermis, they signal your fibroblasts (the cells responsible for producing structural proteins) to wake up and start working more efficiently. This isn't about adding a foreign substance to fill a gap; it is about providing your skin with the biological "blueprints" it needs to repair and renew itself.
At Retriva, our medical-led approach ensures that we utilise only the highest-grade, CE-marked polynucleotide products. This commitment to clinical excellence means you receive a treatment that is both safe and scientifically proven to deliver results.
The primary function of Polynucleotides is biostimulation. Once administered, they perform several critical roles:

Many of our patients come to us asking for dermal fillers or anti-wrinkle injections. While these treatments have their place, we often suggest starting with Polynucleotides. Why? Because the quality of your "canvas": your skin: determines the success of every other treatment.
By improving skin density, elasticity, and hydration first, we find that:
This aligns perfectly with our anti-ageing and skin revitalisation philosophy: we treat the skin as a living organ that deserves long-term care, not just a quick cosmetic fix.
It is a common misconception that all injectables are "fillers." In reality, Polynucleotides and fillers serve very different purposes.
Think of fillers as the architectural support of a building, and Polynucleotides as the restoration of the building’s material itself. For many of our Chelsea-based clients, the goal is to look refreshed and well-rested without anyone knowing they’ve had a "procedure." Polynucleotides deliver exactly that.
One of the reasons we are so fond of Polynucleotides at Retriva is their versatility. They are particularly effective in areas where the skin is thin and delicate: areas that are often difficult to treat with traditional methods.
This is perhaps the most popular use for Polynucleotides. They are exceptional at treating hollow tear troughs, dark circles, and fine "crows's feet." Because they do not attract excessive water like some fillers can, they carry a much lower risk of puffiness or swelling in the delicate eye area.
For patients noticing deep lines and wrinkles or a loss of firmness along the jawline, Polynucleotides provide a subtle "lifting" effect by tightening the skin’s internal structure. They are also excellent for the "necklace lines" that often appear on the neck.
Because of their regenerative properties, Polynucleotides are a powerful tool in our acne treatments. They help to remodel scar tissue and improve the overall smoothness of the skin’s surface.

Every journey at Retriva Aesthetic Clinic begins with a comprehensive, 360-degree assessment. We do not believe in one-size-fits-all protocols. Your skin is unique, and your treatment plan should be too.
During your consultation, our medical experts will examine your facial anatomy, skin quality, and discuss your specific concerns. We will determine if Polynucleotides are the right starting point for you or if a combination of non-surgical lifting and biostimulation would yield the best results.
Your comfort and safety are our highest priorities.

Polynucleotides are a marathon, not a sprint. While some patients notice an improvement in hydration within a week, the true remodelling of the skin takes time.
We generally recommend an initial course of three treatments, spaced 3 to 4 weeks apart. This allows the biological cumulative effect to take hold. Most patients report significant improvements in skin firmness and radiance after the second session, with full results peaking around 3 months after the final treatment.
To maintain your results, a single "top-up" session every 6 to 9 months is usually sufficient. This keeps your skin in a constant state of regeneration, supporting your long-term skin health.
Choosing a clinic for injectable treatments should always be based on medical expertise. At Retriva, all treatments are medical-led, meaning they are performed by qualified practitioners who understand the intricate anatomy of the face.
We utilise advanced techniques to minimise bruising and maximise patient comfort. Our commitment to safety extends beyond the treatment room; we provide comprehensive aftercare advice to ensure your skin heals beautifully and your results are optimised.
For detailed information on our fees, you can view our treatment pricing page.
The "quick fix" is a thing of the past. The future of aesthetics lies in restoration, health, and natural refinement. Polynucleotides offer a unique opportunity to invest in the biological quality of your skin, ensuring it looks as vibrant as you feel.
Whether you are just starting your aesthetic journey or looking to enhance your current regimen, Polynucleotides provide a sophisticated, evidence-based foundation for beautiful skin.

We invite you to experience the Retriva difference. Located in the heart of Chelsea, our clinic provides a serene, professional environment where your goals are our priority.
Book your personalized consultation today and discover how Polynucleotides can unlock your skin's natural potential.
020 3989 6009
07942 355093
Retriva Aesthetic Clinic
250 King's Road, Chelsea, London SW3 5UE